MtDNA testing comparison chart
From ISOGG Wiki
For guidelines on DNA testing see the Genetic genealogy standards.
This chart is provided for informational purposes only. Edits/additions can be made upon ISOGG member request and subject to approval. Please submit additions, corrections/updates to .
|Company name||23andMe|| BritainsDNA ScotlandsDNA IrelandsDNA YorkshiresDNA CymruDNAWales
Chromo2 Complete test
|Family Tree DNA||Full Genomes Corporation||Genebase|| Genographic Project
Geno 2.0 Next Generation test
|Method||Chip-based genotyping||Chip-based genotyping||Next generation sequencing 2000x coverage||Next generation sequencing 50x coverage||Sanger sequencing?||Chip-based genotyping||Sanger sequencing?|
|Main purpose of test|| Health: carrier status, disease risks, drug response (Canada, UK and Ireland only at this time)
Ancestry: DNA Relatives, global origins, ancestral haplogroups
|Deep ancestry||Genealogy||Y-SNP discovery||Genealogy||Deep ancestry||Anthropological testing: patrilineal and matrilineal haplogroups; biogeographical analysis|
|HVR1 only||Not available||Not available||No longer available||Not available||$119||Not available||£199 ($312)|
|HVR1+HVR2||Not available||Not available||$69||Not available||$189||Not available||Not available|
|HVR1 bases tested||Selected branch-defining SNPs||Selected branch-defining SNPs||16001-16569||Not applicable||16001-16520||Selected branch-defining SNPs||16001-16400|
|HVR2 bases tested||Selected branch-defining SNPs||Selected branch-defining SNPs||1-574||Not applicable||1-400||Selected branch-defining SNPs||Not tested|
|Entire mtDNA genome (HVR1, HVR2 + coding region = 16569 bases)||No||No||$199||$999||$528||No||No|
|Haplogroup SNP test (for HVR1+HVR2 tests only)||Not applicable||Not applicable||Included in the cost of the HVR1+HVR2 test||Not applicable||Included in the cost of the HVR1 + HVR2 test||Not applicable||Yes|
|Chip test||$99 for the lifetime of the platform in the US (ancestry only; health reports discontinued in November 2013); CAD $199 or £125 for health and ancestry reports (Canada, Britain and Ireland only at this time)||$369 US (£220 or €269) for females; $399 US (£250 or €309) for males||Not applicable||Not applicable||Not applicable||$199.95 US (£127) ||Not applicable|
|Number of mtDNA SNPs tested (for chip tests only)||2737||Over 3000||Not applicable||Not applicable||Not applicable||~4000 positions on the mtDNA genome||Not applicable|
|Shipping charges||$14.95 for the first kit and $5 per kit for additional kits in the US; $79.95 for the UK; price for other countries varies, but tends to range between $66.95 and $94.95. See shipping DNA kits for further info.||Included in the cost of the kit in the UK; £13 for the Republic of Ireland (includes return courier service)||$12.95 for USA and international orders (prepaid return postage is included for US kits)||$25 for the US; $39 for international orders||Regular delivery, approximately 7 to 10 business days - $10.00 USD. Express delivery, 1 to 2 business days - $25.00 USD||None for the US; $10 for Canada; $20 for Europe and Australia; $50 for all other countries||?|
|International product availability||56 countries||Worldwide||Worldwide||Worldwide||Worldwide||Worldwide?||Worldwide?|
|DNA sample storage||Yes, indefinitely||Yes, indefinitely||Yes, for a miminum of 25 years||No, but the option might be added in the future||Yes, for 25 years||Yes, for 25 years if the free transfer to FTDNA is used||No|
|Phylotree Build||Build 7||?||Build 14||Build 15||?||Build 13 or 14||?|
|Raw data/FASTA file provided||Yes||?||Yes||?||?||No||?|
|Projects supported||No||No||Yes||No||No||Yes, if the free transfer to FTDNA is used||No|
|Online community or forum||Active online community for 23andMe members, including demo accounts||No||Public FTDNA forums||Results can be discussed in the private Full Genomes Facebook group||?||No, but stories about one's Y patrilineal and matrilineal ancestry can be posted on the website for others to view, so add your contact information to them.||?|
|Genealogical matching database||For autosomal DNA only||No||Yes||No||Yes||No||?|
|Size of mtDNA matching database||Not applicable||Not applicable||~ 200,000||Not applicable||Not known||Not applicable||Not known|
|Sponsored public database||No||No||Yes, Mitosearch (for HVR1+HVR2 results) and mtDNACommunity (for full sequence results)||No||No||No||No|
|Additional DNA testing options available from this company||No||Yes, Y-SNP testing, biogeographical analysis and red hair test||Yes, multiple options for Y chromosome STR testing, single SNP tests, and autosomal genome wide scans||No||Yes, multiple options for Y chromosome STR testing, some Y-SNP testing||No||Yes, Limited Y-STR testing|
|Lead scientists in the company||Joanna Mountain, Steve Lemon||James Wilson||Michael Hammer, Connie Bormans||?||Spencer Wells||Bryan Sykes|
|Outside consultants for the company||Itsik Pe’er, Peter Underhill, Serafim Batzoglou, George Church, Michael Eisen, Marcus Feldman, Daphne Koller, Stanley Nelson, Jonathan Pritchard||Not applicable||Bruce Walsh, Doron Behar, Spencer Wells||Greg Magoon||?||Connie Bormans, Eran Elhaik, Thomas Krahn, Elliott Greenspan||Not applicable|
|Ownership||Privately held by various investors, particularly Anne Wojcicki, Johnson & Johnson Development Corp., The Roche Venture Fund, Google Ventures, and New Enterprise Associates||The Moffat Partnership|| Gene by Gene
Managing partners Bennett Greenspan and Max Blankfeld
|Privately held||?|| National Geographic
is a "non-profit scientific and educational society"
| Oxford Ancestors Ltd|
Directors: Bryan Sykes, Susan Foden and William James
|Lab(s) used|| National Genetics Institute
(a subsidiary of LabCorp), Los Angeles, California
|Source Bioscience, Nottingham, England||Family Tree DNA Genomics Center, Houston, Texas||BGI China||Genetrack Biolabs||Family Tree DNA Genomics Center, Houston, Texas||Oxford Ancestors Laboratory, Kidlington, Oxfordshire|
|Method for collecting the sample||Saliva sample (about 1 cc)||Saliva sample||Cheek swab||Saliva sample or cheek swab||Cheek swab||Cheek swab||?|
1390 Shorebird Way
| The Moffat Partnership Limited
60 York Street
Glasgow G2 8JX
| Family Tree DNA
1445 North Loop West
| Full Genomes Corporation Inc
2275 Research Blvd
| Genebase Systems Inc
BC V5R 5T5
| The Genographic Project
1145 17th St. N.W.
Washington, D. C.
| Oxford Ancestors|
PO BOX 841
Oxfordshire OX1 9LJ
|Contact||FTDNA Contact Form|
|Phone number||Enter a ticket online at customer care for a call-back||0845 872 7634||713-868-1438||All communications are via e-mail||1-604-714-6357||888-557-4450 (in the US or Canada) or 713-868-1807||0845 5438060|
|Year founded||2006||2011 (2004)||2000||2012||2005 (1998)||2005||2000|
- The companies now trading as BritainsDNA, ScotlandsDNA, IrelandsDNA, YorkshiresDNA and CymruDNAWales were formerly known as Ethnoancestry. The Chromo2 test was launched in June 2013.
- Family Tree DNA also processes tests for a number of affiliate companies: African DNA, iGENEA, DNA Ancestry & Family Origin and DNA Worldwide. Participants who join Family Tree DNA's database from these companies will have kit numbers that begin with 'A' from African DNA, 'E' from iGENEA, 'M' from DNA Ancestry & Family Origin, and 'U' from DNA Worldwide. National Geographic Genographic kit transfers begin with 'N'. Family Tree DNA acquired DNA Heritage in April 2011. DNA Heritage customers were given the option of transferring their results to the FTDNA database. DNA Heritage kit numbers begin with the letter 'H'.
- The Geno 2.0 test was launched in the fall of 2012. Geno 2.0 Next Generation went on sale in August 2015.
- Canada RA. How do you perform mtDNA mitochondrial DNA) tests? FAQ, Family Tree DNA Learning Center, 1 January 2014
- FTDNA discontinued the HVR1 test in May 2013
- Exchange rate checked on 21 August 2015
- This test is known as the full mitochondrial sequence (FMS) test. It was previously referred to as the full genomic sequence (FGS) or mega test.
- The Full Genome test is primarily a full Y-chromosome sequence test which reports on all known Y-SNPs plus an unpredictable number of novel Y-SNPs and 300+ Y-STRs. The full mtDNA sequence is included in the test as a bonus, and provides 95% or greater coverage of the mt genome depending on the sample.
- Editorial Staff. "Are the mitochondrial DNA (mtDNA) haplogroups predicted or confirmed?" Family Tree DNA Learning Center, Gene by Gene. Retrieved 2014-15-05.
- mtDNA testing is not available as a standalone product but is included in the Chromo2 test. The male test is more expensive because it includes Y-SNPs. Currency conversions extracted from the BritainsDNA website in August 2015.
- The Genographic Project's Geno 2.0 Next Generation test uses a custom-designed Illumina Express chip which tests around 750,000 markers, including around 4000 mtDNA SNPs, and around 20,000 Y-SNPs. The full specifications for the test are not yet available.
- The original Geno 2.0 test had 11,378 probes covering 3281 positions on the mtDNA genome.
- Editorial Staff. "Shipping DNA tests worldwide". Family Tree DNA Learning Center. Gene by Gene. https://www.familytreedna.com/learn/ftdna/shipping-dna-tests-to-international-destinations/. Retrieved 2016-5-24.
- The mtDNA tree is maintained by Phylotree. The current version is Build 16.
- About the Family Tree DNA database Family Tree DNA website. Accessed 9 November 2013.
- 23andMe Scientific Advisory Board
- Who's who at Family Tree DNA
- Beta-testing is also being done at UCLA (University of California, Los Angeles) but they have not as yet been confirmed as a sequencing provider.
- The company was founded in 2004 as Ethnoancestry, and relaunched as ScotlandsDNA in 2011. The trade names BritainsDNA, IrelandsDNA and YorkshiresDNA were added in 2012.
- Genebase launched in 2005. Genetrack Biolabs launched in 1998. (http://www.genebase.com/about/?p=3)
- Before You Buy
- Beginners' guides to genetic genealogy
- Choosing a DNA testing company
- Mitochondrial DNA portal
- Mitochondrial DNA tests
- List of mtDNA haplogroup projects
- mtDNA tools
- Shipping DNA kits
- Understanding genetic ancestry testing
- Coakley L. Which DNA testing company should I use? Genie! blog (a review from the perspective of people living in Australia and New Zealand]
- Griffith S. Buyer beware links. Genealogy Junkie, 14 May, 2014.
- Griffith S. Notes for UK (& Ex-US) residents re DNA testing companies. Genealogy Junkie, 16 January 2014.
- Kennett D. Mitochondrial DNA testing at a new low price. Cruwys News blog, 10 May 2013.
- MacArthur D. Ready to test your DNA: how to choose a genetic testing company. PRI's The World, 22 March 2012.
- Aulicino E. Which DNA testing company fits your needs? Genealem blog, 23 May 2009.
- Wagner JK, Cooper JD, Sterling R, and Royal CD. Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests. Genetics in Medicine 2012:14(6):586–593. The article provides a snapshot of the direct-to-consumer DNA ancestry testing industry in April 2010 based on a survey of company websites.
- DNAtestingchoice.com A DNA testing review website
23andMe, BritainsDNA, DNA Ancestry & Family Origin, Family Tree DNA, Full Genomes Corporation, iGENEA, Genebase, IrelandsDNA, National Geographic Genographic, Oxford Ancestors, ScotlandsDNA and YorkshiresDNA are registered, trademarked, and/or copyrighted names of companies, websites and organizations, not affiliated with ISOGG.