From ISOGG Wiki
(Redirected from Deep clade tests)
SNP testing is required to confirm haplogroup assignments, to learn more about your deep ancestry and to rule out false positive matches. Y-SNP chip tests are available from the Genographic Project and BritainsDNA. More comprehensive sequencing tests using next generation sequencing technology are available from Full Genomes Corporation and Family Tree DNA. Single SNPs and SNP panels can be ordered from Family Tree DNA and YSEQ.
There are currently two companies that offer single SNPs.
Family Tree DNA offer a range of single SNPs at US $39 per SNP. SNPs can only be ordered by existing FTDNA customers who have already taken a Y chromosome DNA test with the company. In October 2013 over 3500 individual SNPs were available to order from FTDNA. The placement on the phylogenetic tree is unknown for most of them. SNPs with a known placement are highlighted in the customer's personal results page under the Y-DNA Haplotree & SNPs section. Customers can also request that new SNPs are added to the catalogue.
YSEQ is a company established by Thomas and Astrid Krahn in November 2013. YSEQ offers a potentially unlimited menu of single SNPs at US $17.50 per SNP. For further details of this company see the blog post by Debbie Kennett entitled YSEQ a new company offering single SNPs.
Checking for similarity mainly to X and primer development using +/-500bp: up to 90% is good, up to 95% possible - http://genome.ucsc.edu/cgi-bin/hgBlat?command=start
SNP panels (formerly known as deep clade tests) are available from YSEQ and Family Tree DNA. Many of these panels are still under development. It is best to check with the volunteer administrators of the relevant haplogroup project before ordering any such test.
The old deep clade tests from Family Tree were withdrawn from sale in January 2013.
Next generation sequencing
Next generation sequencing tests are the most advanced SNP tests available on the market and can be used for SNP discovery. There are currently two products available for the genetic genealogy market: the Big Y test from Family Tree DNA and the Y Elite 2.0 test from Full Genomes Corporation.
- The future of comprehensive Y testing is here by Kelly Wheaton. Lesson 15: Beginners' Guide to Genetic Genealogy.
- Why SNP testing is important by Robert Casey
- How To - Y-SNPs (Genealogical Viewpoint) by Robert Casey
- How To - Y-SNPs (Deep Ancestry Viewpoint) by Robert Casey
- How To - Y-SNPs (Future Trends) by Robert Casey
- The full Y-chromosome sequencing economic challenge A diagram prepared by Michael Walsh.
- Why SNP? Article published on the ISOGG website, 16 January 2008.
FTDNA Learning Center articles
- How to figure out what Y SNPs are tested at 23andme by Kitty Cooper, Kitty Cooper's blog, 23 February 2014.
- A confusion of SNPs by Debbie Kennett, Cruwys News blog, 15 November 2013.
- A simplified Y-tree and a common standard for Y-DNA haplogroup and SNP nomenclature by Debbie Kennett, Cruwys News blog, 8 November 2013.
- The changing names of Y-DNA by Judy Russell, The Legal Genealogist blog, 27 January 2013
- To SNP or not to SNP by Roberta Estes, DNAeXplained blog, 10 August 2012
- Using SNP testing and STRs to enhance a genetic genealogy research project. A re-recording of a presentation given by John Cleary at Who Do You Think You Are? Live in April 2016. The presentation is split into three parts:
- Y-SNPs - key to the future. a presentation by Robert Casey explaining the importance of SNP testing.
- List of Y-DNA haplogroup projects
- Y-DNA project help
- Y-DNA SNP testing chart
- Y-DNA STR testing chart
- Y-DNA next generation sequencing chart
- Walk Through the Y
- Why SNP?
- The price was raised from $29 per SNP to $39 per SNP in January 2013.
- The price was lowered from $35 per SNP to $17.50 per SNP in February 2015.
- "Exciting new developments at FTDNA". E-mail from Family Tree DNA to Y-DNA haplogroup project administrators, 25 January 2013.