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Base pair

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Public domain logo This image is taken from the Talking Glossary of Genetic Terms and is reproduced courtesy of the National Human Genome Research Institute.

A base pair is two chemical bases bonded to one another forming a "rung of the DNA ladder". The DNA molecule consists of two strands that wind around each other like a twisted ladder. Each strand has a backbone made of alternating sugar (deoxyribose) and phosphate groups. Attached to each sugar is one of four bases - adenine (A), cytosine (C), guanine (G), or thymine (T). The two strands are held together by hydrogen bonds between the bases, with adenine forming a base pair with thymine, and cytosine forming a base pair with guanine.

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Public domain logo

This article uses material in the public domain from the Talking Glossary of Genetic Terms and is reproduced courtesy of the National Human Genome Research Institute.